All other comparisons failed to reach significance. hBDNF Val66Met genotype does not alter NMDA receptor subunit expression Given the role of PSD-95 as a scaffolding protein involved in securing NMDA receptors to the cell membrane, 49 that BDNF Val66Met genotype is associated with altered NMDA receptor physiology 50 , 51 , 52 and that NMDA receptor subunits may modulate FST performance, 53 , 54 , 55 we next screened for differences in expression of the NMDA receptor NR2A, NR2B and NR1 subunits.
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The BDNF Val66Met polymorphism regulates glucocorticoid-induced corticohippocampal remodeling and behavioral despair.
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