There was a positive trend between CD3 + T cell IP and multiple other markers, although not significant at the P = 0.05 level, including: time to peak diversity (Spearman’s ρ = 0.44, P = 0.22), time to CD4 + T cell count < 200 (Spearman’s ρ = 0.55, P = 0.21), time to detection of the X4-tropic genotype (Spearman’s ρ = 0.09, P = 0.77), and time to peak representation of the X4-genotype (Spearman’s ρ = 0.71, P = 0.14) ( S9I–S9L Fig ).
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Patterns and rates of viral evolution in HIV-1 subtype B infected females and males.
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