a marginal trendp = 0.057
Although there was a marginal trend for increased Ntcp1 mRNA in BAE mice ( p = 0.057) suggesting a higher hepatic bile acid clearance from the portal vein, there was no apparent effect on genes involved in the canalicular secretion to the biliary duct ( Bsep, Abcg8, Abcc2 ), export of bile acids to the circulation ( Abcc3, Abcc4 ) or Fxr in the liver.