The conjugated antimetabolite 5-FdU-ECyd and its cellular and molecular effects on platinum-sensitive vs. -resistant ovarian cancer cells <i>in vitro</i>.

Oncotarget · 2017 · PMC5652753 · PMID 29100359

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Immunofluorescence analysis confirmed these findings and demonstrated a highly significant increase in the average number of γH2AX foci per cell in 5-FdU-ECyd treated A2780, A2780cis and Skov-3-IP cells, compared to untreated controls (Figure 4B, 4C ).

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