Histone deacetylase inhibitors vorinostat and panobinostat induce G1 cell cycle arrest and apoptosis in multidrug resistant sarcoma cell lines.

Oncotarget · 2017 · PMC5652778 · PMID 29100385

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highly significantno p-value reported

SAHA treatment caused a highly significant increase in the number of cells in G1 phase compared to controls in both SW-982 and SW-1353 cells, which was accompanied by a decrease in the number of S phase cells, indicating a G1/S phase arrest.

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