Down-regulation of traditional oncomiRs in plasma of breast cancer patients.

Oncotarget · 2017 · PMC5652785 · PMID 29100393

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a decreasing trendno p-value reported

Similarly, different expression of miR-21 in tissues from atypical ductal hyperplasia, DCIS and DIC compared to normal breast was previously shown; however, with the increasing values during the tumor progression [ 51 ], that is in contrast to a decreasing trend in plasma from patients with non-invasive to patients with invasive BC in our study.

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