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The evidence base for circulating tumour DNA blood-based biomarkers for the early detection of cancer: a systematic mapping review.

BMC Cancer · 2017 · PMC5654013 · PMID 29061138

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The sentences

an encouraging trendno p-value reported
There is an encouraging trend towards larger, more ambitious studies, supported by the commercial sector (e.g.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.