Change in risk of breast cancer after receiving hormone replacement therapy by considering effect-modifiers: a systematic review and dose-response meta-analysis of prospective studies.

At the same time, we found a non-linear association ( P non-linearity < 0.001) (Figure 3A ) between use time and BC risk, suggesting that an increasing trend displayed in first 5-year use and became gentle after that.

also in 63,971 other papers