γc cKO IL-6 KO IFN-γR KO mice) caused highly significant reductions in both SP8 frequency and number ( Fig. 3b ), suggesting that these cytokines had overlapping effects in vivo .
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Identification of lineage-specifying cytokines that signal all CD8<sup>+</sup>-cytotoxic-lineage-fate 'decisions' in the thymus.
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