In addition, our literature survey revealed that ultrasound also downregulated three major histocompatibility complex (MHC)-related highly significant immunogenic/pro-inflammatory genes with the decreased fold changes from −5.9 to −32.5 (Hundt et al., 2008 ) (not shown).
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Low-Intensity Ultrasound-Induced Anti-inflammatory Effects Are Mediated by Several New Mechanisms Including Gene Induction, Immunosuppressor Cell Promotion, and Enhancement of Exosome Biogenesis and Docking.
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