As those amino acids lost their significance or some remained marginally significant for the association with gout after further adjustment of the model for the variable gender, this might have been caused by the fact that a small number of female patients with gout could be included in this study.
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Alteration in plasma free amino acid levels and its association with gout.
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The sentences
Nonetheless, as we believe, the role of those amino acids in gout should not be underestimated as they showed highly significant differences between the patient and control groups in this study and also in a number of studies as discussed earlier.