Microglia and Monocytes/Macrophages Polarization Reveal Novel Therapeutic Mechanism against Stroke.

In contrast, the microglial M2-like response increased on day 1 and exhibited an increasing trend in the first 14 days ( Figure 2 b).

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Post-hemorrhagic temporal analysis of microglial phenotypes demonstrated that M1-like microglia and monocytes/macrophages increased acutely as early as 6 h after hemorrhagic stroke, and exhibited a decreasing trend in the first 14 days after hemorrhagic stroke [ 22 , 74 ].

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