Barely Significant
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Assessing the reliability of spike-in normalization for analyses of single-cell RNA sequencing data.

Genome Res · 2017 · PMC5668938 · PMID 29030468

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This is expected because genes on the borderline of significance are more susceptible to random fluctuations in the size factors.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.