Nonetheless, patients who possess TP53 mutation(s) and elevated levels of MDM2 at the same time (21 cases, 14%) exhibit a decreasing trend in the survival rate compared to others, yet devoid of statistical significance (Figure 1F ).
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Molecular chaperones in the acquisition of cancer cell chemoresistance with mutated <i>TP53</i> and MDM2 up-regulation.
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