Proteomic analysis reveals novel ligands and substrates for LNX1 E3 ubiquitin ligase.

PLoS One · 2017 · PMC5679597 · PMID 29121065

Europe PMC DOI

hedged sentences

—

closest p

—

boldest claim

The sentences

did not quite reach statistical significanceno p-value reported

This increase did not quite reach statistical significance but statistically significant increases in ubiquitination of liprin-α1 were observed in immunoprecipitates from cells transfected with the neuronal LNX1p70 isoform ( p < 0.05), which lacks the RING finger domain required for ubiquitination, and LNX2 ( p < 0.05), compared to the control vector ( Fig 3B , upper graph).

also in 679 other papers

may not be significantno p-value reported

Thus, some interaction pairs that have been identified by yeast-two-hybrid or protein/peptide arrays may not be significant in a mammalian cellular context in which many potential ligands are binding competitively to LNX proteins.

also in 2,774 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.