Cell growth kinetics revealed a slight trend toward decreasing proliferation potential with age ( Fig. 2B ).
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Adipose-Derived Mesenchymal Stem Cells from the Elderly Exhibit Decreased Migration and Differentiation Abilities with Senescent Properties.
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Consistent with these results, a decreasing trend of c-Jun and c-Fos gene expression, the key proto-oncogenes related to proliferation, with age was observed ( Fig. 2C ).