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Identifying functional network changing patterns in individuals at clinical high-risk for psychosis and patients with early illness schizophrenia: A group ICA study.

Neuroimage Clin · 2018 · PMC5681342 · PMID 29159045

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a decreasing trendno p-value reported
Indeed, the co-activation of these regions also showed a decreasing trend from HCs to CHR individuals to ESZ patients, supporting the possible role of these regions as biomarkers of clinical severity.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.