<i>Escherichia coli</i> Nissle 1917 engineered to express Tum-5 can restrain murine melanoma growth.

Oncotarget · 2017 · PMC5689645 · PMID 29156755

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extremely significantno p-value reported

A difference with a P value of less than 0.05 was considered statistically significant, whereas P <0.01 was considered extremely significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.