Smoking and gender modify the effect of <i>TWIST</i> on patient survival in head and neck squamous carcinoma.

Oncotarget · 2017 · PMC5689649 · PMID 29156759

Europe PMC DOI

hedged sentences

0.0580

closest p · 1.2× alpha

0.0580

boldest claim

The sentences

borderline significantp =0.058so close (0.05 < p ≤ 0.1)

When patients were stratified by either gender or smoking status, those with high TWIST1 had significantly elevated risk of death compared to those with low TWIST1 in male (HR = 1.59, 95% CI: 1.12 – 2.25) (p = 0.010) and borderline significant elevated risk in smoker (HR = 1.38, 95% CI: 0.99 – 1.94) (p =0.058) subgroups (Table 4 ) after adjusting covariates.

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borderline significanceno p-value reported

Results Survival analyses showed that high TWIST1 expression was associated with a poor overall survival at a borderline significance level, while a superior but not statistically significant overall survival was observed in high TWIST2 expression.

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