showed that modest changes in pH (a difference of pH 7.8 to 6.8) produced marked, highly significant decreases in macropinocytic efficiency in the human epidermoid carcinoma cell line A431, whereas in some cases the uptake of biomolecules was largely unaffected at a pH of 6.8 and much more acidic values had to be reached before a sizable inhibition of macropinocytosis was detected [ 24 ].
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Amiloride-enhanced gene transfection of octa-arginine functionalized calcium phosphate nanoparticles.
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