13 In Europe, an increasing trend of trisomy 13, 18, and 21 between 1990 and 2009 has been reported. 9 In Korea, most prenatal screening methods are available, such as the first trimester combined test, Quad screening, integrated, sequential test, and cell-free DNA screening. 26 However, legally acceptable pregnancy termination is very restricted in Korea.
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A national cohort study evaluating infant and fetal mortality caused by birth defects in Korea.
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