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The mechanisms of humic substances self-assembly with biological molecules: The case study of the prion protein.

PLoS One · 2017 · PMC5697873 · PMID 29161325

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may be significantno p-value reported
Changes in prion structure upon environmental exposure may be significant as they can affect prion infectivity and disease pathology.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.