Barely Significant
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RNA metabolism is the primary target of formamide in vivo.

Sci Rep · 2017 · PMC5698326 · PMID 29162938

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highly significantp-value = 0.001actually significant
AnGeLi results showed a highly significant enrichment in RNA metabolism related genes (p-value = 0.001) and respective hierarchical GOs (Fig. 5e ) 42 .

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