Levodopa-induced abnormal involuntary movements correlate with altered permeability of the blood-brain-barrier in the basal ganglia.

This quantitative analysis revealed highly significant overall differences between groups and sample areas (Group: F (1,40) = 38.89; p < 0.0001; Area: F (3,40) = 7.9; p = 0.0003; Interaction: F (3,40) = 3.2; p = 0.0332).

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