[ 17 ] also reported a statistically significant increase in trough FEV 1 with UMEC/VI compared with twice-daily administration of aclidinium/formoterol, as well as a nonsignificant trend favoring UMEC/VI over TIO/OLO.
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Comparative Efficacy of Once-Daily Umeclidinium/Vilanterol and Tiotropium/Olodaterol Therapy in Symptomatic Chronic Obstructive Pulmonary Disease: A Randomized Study.
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