Randomized Clinical Trial to Evaluate the Efficacy and Safety of Combination Therapy with Short-Pulsed 1,064-nm Neodymium-Doped Yttrium Aluminium Garnet Laser and Amorolfine Nail Lacquer for Onychomycosis.

Although cumulative cure rate, change of infected area and patient satisfaction are not standard evaluation methods for onychomycosis therapy, we could suggest a positive trend of treatment response.

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In our clinical trial, using changes in lesion-free area as the primary endpoint showed borderline significance.

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Using cure rate as a key secondary endpoint showed highly significant results in the test group compared to the control group.

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