We confirmed these results in HepG2-HBx cells: exposure 50 or 100 μM Nar yielded significant decreases in the accumulation of PPARγ and LXRα mRNAs, while the effects on Srebp-1c transcript levels did not achieve significance (Fig. 4b ).
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Naringenin attenuates hepatitis B virus X protein-induced hepatic steatosis.
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