In the recombinants of serotype 1, the deleted type-specific sequences mapped predominantly to the region spanning between the capsid genes and internal parts of the 3D pol gene, with an apparent trend to retain, in some cases, their own 3ABC and surrounding sequences, suggesting the possibility that there are two most likely regions undergoing removal located around the 2B/2C and 3C/3D borders respectively ( Figure 1 A).
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Pressure for Pattern-Specific Intertypic Recombination between Sabin Polioviruses: Evolutionary Implications.
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