Characterizing the heterogeneity of tumor tissues from spatially resolved molecular measures.

PLoS One · 2017 · PMC5708750 · PMID 29190747

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a decreasing trendno p-value reported

Its average value increased with stage in grade 1 tumors, then it stayed relatively unchanged for grade 2, followed by a decreasing trend with stage for grade 3 tumors.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.