Transcriptomic profiling of mTOR and ryanodine receptor signaling molecules in developing zebrafish in the absence and presence of PCB 95.

We chose ryr3 because it experiences a highly significant increase in transcription between 24 and 72 hpf as well as between 24 and 120 hpf, and because of discrepancies in the published data, which describe ryr3 transcription in zebrafish prior to 24 hpf in skeletal muscle only, or predominantly in hindbrain regions at later time points ( Thisse & Thisse, 2005 ; Wu, Brennan & Ashworth, 2011 ).

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