Activity alterations in the bed nucleus of the stria terminalis and amygdala during threat anticipation in generalized anxiety disorder.

As indicated in Figure 3 , the mean statistical values for the contrast threat minus neutral anticipation in GAD patients as compared to HC extracted from the overlapping cluster of all significant Sustained Response GLMs, followed a highly significant quadratic function with the delay of the sustained response predictor (function: y = −0.022 x 2 + 0.297 x + 2.291, R 2 = 0.96, P < 0.007).

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