Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.

CD, MOSGWA selected 14 SNPs, including rs17659990 (P=5.43×10 -9 , DOCK3 ) that reached the generally accepted level of genome-wide significance, followed by borderline significant rs7742915 (P=8.52×10 -8 , BTBD9 ), rs16944613 (P=1.49×10 -7 , CRTC3 ), rs13129679 (P=2.38×10 -7 , RNF4 ) and rs12953717 (P=3.00×10 -7 , SMAD7 ), a well-known CRC susceptibility variant.

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