The <i>NDE1</i> genomic locus can affect treatment of psychiatric illness through gene expression changes related to microRNA-484.

Open Biol · 2017 · PMC5717342 · PMID 29142105

Europe PMC DOI

hedged sentence

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closest p · 0.0× alpha

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highly significantp = 2.3 × 10 −10actually significant

The first of these, TRIOBP , was observed to be significant in our discovery cohort but not in the replication cohorts, while the other is NDE1 itself, which was highly significant in the larger GTEx database (β = 0.24; s.e. = 0.037; t -statistic = 6.6; p = 2.3 × 10 −10 ), but not originally observed in our discovery cohort.

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