Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution.

Cell · 2017 · PMC5720478 · PMID 29107330

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highly significantp = 1.36e-115actually significant

We observed a highly significant relationship between the minor and major allele copy-number estimates obtained from LOHHLA and ASCAT (p = 1.36e-115, rho = 0.70, Spearman’s rank test; Figures 1 B and S1 A), supporting the utility of LOHHLA to accurately estimate copy number and LOH.

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