For those significant outcomes, the further adjustment for major and minor ECG abnormality did not substantially attenuate the associations, although the relationship to HF became borderline significant (model 4).
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Counterclockwise and Clockwise Rotation of QRS Transitional Zone: Prospective Correlates of Change and Time-Varying Associations With Cardiovascular Outcomes.
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On the contrary, counterclockwise rotation was significantly related to lower risk of composite CVD (hazard ratio, 0.93; 95% CI, 0.87–0.99]), CVD mortality (hazard ratio, 0.76; 95% CI, 0.65–0.88), and non‐CVD deaths (hazard ratio, 0.92; 95% CI, 0.85–0.99 [borderline significance with heart failure]).