Genetic Variants Associated With Uncontrolled Blood Pressure on Thiazide Diuretic/β-Blocker Combination Therapy in the PEAR (Pharmacogenomic Evaluation of Antihypertensive Responses) and INVEST (International Verapamil-SR Trandolapril Study) Trials.

J Am Heart Assoc · 2017 · PMC5721751 · PMID 29097388

Europe PMC DOI

hedged sentence

0.1040

closest p · 2.1× alpha

0.1040

boldest claim

The sentences

a trend toward significanceP =0.104not close (p > 0.1)

rs261316 showed a trend toward significance in the INVEST white–Hispanic meta‐analysis (OR: 1.22, 95% CI, 0.94–1.59, P =0.104), with the association driven by INVEST Hispanics only (OR: 1.56, 95% CI, 1.05–2.32, P =0.030).

also in 3,729 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.