Multiple treatment comparison of seven new drugs for patients with advanced malignant melanoma: a systematic review and health economic decision model in a Norwegian setting.

BMJ Open · 2017 · PMC5724191 · PMID 28827234

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a decreasing trendno p-value reported

The monotherapies showed a decreasing trend for further increasing WTP values, contrary to the combination strategies.

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an increasing trendno p-value reported

When dacarbazine is excluded, the BRAF and MEK inhibitors in monotherapy had the highest probability of being cost-effective for the lowest WTP values and the combination strategies showing an increasing trend for very high WTP values.

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