Effects of chronic noise on the corticotropin-releasing factor system in the rat hippocampus: relevance to Alzheimer's disease-like tau hyperphosphorylation.

Results showed that the expression levels of CRF and CRFR1 mRNA and protein in hippocampus were significantly increased after exposure to noise for 30 days, with an increasing trend that persisted for up to 7 days after the final noise exposure (Fig. 2 a–f).

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