Ascorbic acid promotes cardiomyogenesis through SMAD1 signaling in differentiating mouse embryonic stem cells.

PLoS One · 2017 · PMC5726630 · PMID 29232368

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highly significantno p-value reported

These latter data suggest that the phospho-SMAD ratio is tightly regulated during cardiomyogenesis, but that the combined treatment of the cells with both AA and BMP2 can cause a transient and highly significant increase in phospho-SMAD1/5/8.

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