Clinicopathological hallmarks and biomarkers of colorectal neuroendocrine neoplasms.

PLoS One · 2017 · PMC5726657 · PMID 29232390

Europe PMC DOI

hedged sentences

0.0002

closest p · 0.0× alpha

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boldest claim

The sentences

highly significantP = 0.0002actually significant

As demonstrated in Fig 4B , 12 out of 18 (66.7%) patient samples showed a highly significant increase in plasma CgA levels (P = 0.0002) during tumor progression which was in total nearly nine times higher (mean increase of 291.3 U/l) compared to samples derived from patients with NEN of the colon and rectum.

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borderline significantP = 0.05actually significant

Furthermore, metastatic disease was borderline significant as negative predictor for survival (metastatic vs. non-metastatic; 5.3 years vs. not reached; P = 0.05).

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