In essence, NNK’s effects were highly significant through most of the downstream steps; whereas ethanol’s adverse effects were more limited its upregulation of p70S6K and inhibition of its relative phosphorylation.
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Differential Effects of 3rd Trimester-Equivalent Binge Ethanol and Tobacco-Specific Nitrosamine Ketone Exposures on Brain Insulin Signaling in Adolescence.
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