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Identification of <i>SPOP</i> related metabolic pathways in prostate cancer.

Oncotarget · 2017 · PMC5732708 · PMID 29262542

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an increasing trendno p-value reported
The incidence rates of PCa have shown an increasing trend in almost all countries [ 4 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.