Subcutaneous interferon β-1a three times weekly and the natural evolution of gadolinium-enhancing lesions into chronic black holes in relapsing and progressive multiple sclerosis: Analysis of PRISMS and SPECTRIMS trials.

In the DT group only we observed a numerical trend for an association between ≥1 CBH and higher rates of disability progression versus no CBH, suggesting that CBH may be a prognostic factor; however, the utility of CBH for predicting future disability requires further investigation.

also in 1,012 other papers