Preincubation with DMF significantly reduced the EGF-induced association of total Wip1 with RSK2, while the inhibitory effect of DMF on the MIF-induced association of total Wip1 with RSK2 was only borderline significant ( Figure 7B ).
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Protein phosphatase 2Cδ/Wip1 regulates phospho-p90RSK2 activity in lesional psoriatic skin.
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