Second, although the highly significant association between HPSE and the risk of HCC was derived from a biologically-based a priori hypothesis, our initial findings need to be verified independently in other populations with high incidences of HCC, such as other southern Chinese, as well as Singaporeans and Taiwanese.
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Association of polymorphisms in the heparanase gene (HPSE) with hepatocellular carcinoma in Chinese populations.
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