Interestingly, compared to the private DA clonotypes of each patient, higher rate of convergent selection (multiple nucleotide clonotypes coding for identical amino acid clonotype) appears to be a feature of these ‘public subset’ of the DA clonotypes with an increasing trend during gluten exposure (Supplementary Figure S10 ).
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Deep sequencing of blood and gut T-cell receptor β-chains reveals gluten-induced immune signatures in celiac disease.
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