Regarding safety, the increased risk of HF hospitalization with saxagliptin in SAVOR-TIMI 53 ( 6 ) and a nonsignificant trend with aloglipitin in EXAMINE ( 7 , 59 ) resulted in the addition of new safety warnings to the labels of those medications ( 64 ).
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Cardiovascular Outcomes Trials in Type 2 Diabetes: Where Do We Go From Here? Reflections From a <i>Diabetes Care</i> Editors' Expert Forum.
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