a decreasing trendP = 0.3173
However, we observed that the median OS of patients with KRAS G12 V exhibited a decreasing trend compared with those with G12D (25 months vs. 50 months, P = 0.3173), and the same decreasing trend was found between the wild type and the G12D mutation (22 months vs. 50 months, P = 0.1742) (Fig. 2 ).