Features of MRI stromal enhancement with neoadjuvant chemotherapy: a subgroup analysis of the ACRIN 6657/I-SPY TRIAL.

J Med Imaging (Bellingham) · 2018 · PMC5741993 · PMID 29296631

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an increasing trendno p-value reported

SER pattern from the tumor edge and interaction with RFS Using the same mixed effects model as for PE, we observed an increasing trend, rather than a decrease, in mean SER as a function of distance from the tumor edge at the pretreatment time point (T1).

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a decreasing trendno p-value reported

While not statistically significant, we found a decreasing trend in global stromal signal enhancement ratio values with the use of chemotherapy.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.