Barely Significant
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Codeine is associated with poor prognosis in acute stroke.

Brain Behav · 2017 · PMC5745247 · PMID 29299387

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highly significantno p-value reported
The highly significant findings suggest that codeine has a negative effect on acute stroke patients.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.